The electrocardiographic pattern known as circumferential ischemia was described as a sign of left main coronary artery subocclusion or multivessel disease. However, newer studies question this angiographic association, although this sign is associated with higher in-hospital mortality.
Electrocardiographic Criteria
- Diffuse ST-segment depression in 7 or more leads
- ST-segment elevation in aVR and V1
ECG in Circumferential Ischemia

Circumferential ischemia. Patient with chest pain that began a few hours earlier and an ECG showing diffuse ST-segment depression with ST elevation in V1 and aVR.
Related Topics
References
- Birnbaum Y, Bayés de Luna A, Fiol M, Nikus K, et al. Common pitfalls in the interpretation of electrocardiograms from patients with acute coronary syndromes with narrow QRS: a consensus report. J Electrocardiol. 2012;45(5):463–75.
- Alencar JN. Tratado de ECG. 2022.
- Harhash AA, Huang JJ, Reddy S, Natarajan B, et al. aVR ST Segment Elevation: Acute STEMI or Not? Incidence of an Acute Coronary Occlusion. Am J Med. 2019;132(5):622–30.








